Interferon beta-like molecules for treatment of stroke

摘要

The present invention relates to use of interferon beta-like polypeptides for treatment of stroke or transient ischemic attach in a primate, preferably in a human. More particularly, the interferon beta-like polypeptides differs from the amino acid sequence of wild-type human IFNB (SEQ ID NO:2) in that at least one glycosylation site, preferably at least one in vivo N-glycosyltaion site has been introduced. Optionally the interferon beta-like polypeptides are PEGylated.