发明名称 USE OF AROMATASE INHIBITORS FOR ENDOMETRIAL THINNING IN PREPARATION FOR SURGICAL PROCEDURES ON THE ENDOMETRIAL CAVITY AND UTERUS
摘要 Aromatase inhibitors are administered to a female patient prior to endometrial ablation or resection procedures in order to thin the endometrium to a thickness of less than 6 mm, and preferably less than 4 mm, so as to enhance the treatment outcome. Of course, administration of aromatase inhibitors would be useful for other surgical procedures on the endometrial cavity and the uterus. Commercially available aromatase inhibitors, including, the nonsteroidal preparations, anastrozole and letrozole, and a steroidal agent, exemestane, are well-tolerated, and have been shown to decrease serum estrogen levels. The aromatase inhibitor can be used alone, or in combination with other aromatase inhibitors or pharmaceutical agents, such as hormones.
申请公布号 CA2585832(A1) 申请公布日期 2006.04.20
申请号 CA20052585832 申请日期 2005.10.04
申请人 WAYNE STATE UNIVERSITY;MOUNT SINAI HOSPITAL CORPORATION 发明人 MITWALLY, MOHAMED F. M.;DIAMOND, MICHAEL P.;CASPER, ROBERT F.
分类号 A61K38/00;A61K31/56 主分类号 A61K38/00
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