发明名称 |
Modulation of nitric oxide signaling through signaling through specific regulation by arginylation and the N-end rule pathway |
摘要 |
Screening assays that allow for the identification of agents that modulate the activity of the arginylation branch of the N-end rule pathway are provided. Also provided are method of using an agent that modulate the activity of the arginylation branch of the N-end rule pathway to increase or decrease protein degradation in a cell, and to modulate physiologic and pathologic associated with N-end rule pathway mediated arginylation.
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申请公布号 |
US2006084097(A1) |
申请公布日期 |
2006.04.20 |
申请号 |
US20050228157 |
申请日期 |
2005.09.16 |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
HU RONG-GUI;SHENG JUN;KWON YONG T.;KASHINA ANNA;VARSHAVSKY ALEXANDER |
分类号 |
C12Q1/68;C40B40/08;C40B40/10;G01N33/53 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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