发明名称 |
Methods and products related to the intracellular delivery of polysaccharides |
摘要 |
The invention relates, in part, to methods and compositions for the intracellular delivery of polysaccharides. In particular, the methods and compositions relate to the intracellular delivery of glycosaminoglycans, such as heparin. The invention in other aspects relates to the use of glycosaminoglycans for the treatment of proliferative disorders, such as cancer. The invention is still other aspects relates to improving cell viability. The invention also relates to the delivery of polysaccharides while avoiding unwanted effects of the polysaccharides. For example, heparin can be delivered while avoiding its anticoagulant effects.
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申请公布号 |
US2006083711(A1) |
申请公布日期 |
2006.04.20 |
申请号 |
US20050107360 |
申请日期 |
2005.04.15 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
BERRY DAVID A.;ANDERSON DANIEL G.;LYNN DAVID M.;SASISEKHARAN RAM;LANGER ROBERT S. |
分类号 |
A61K31/785;A01N1/02;A61K31/726;A61K31/727;A61K31/737;A61K45/06;A61K47/34;A61K47/48;A61P19/08;A61P27/02;A61P35/00 |
主分类号 |
A61K31/785 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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