| 发明名称 |
Methods for determining precise HERG interactions by mutagenesis |
| 摘要 |
The present invention discloses methods of determining highly precise interactions between the HERG ion channel and various compounds. The methods of the present invention utilize modified HERG ion channels combined with heterologous in vivo expression in Xenopus oocytes and mammalian cells.
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| 申请公布号 |
US2006084102(A1) |
申请公布日期 |
2006.04.20 |
| 申请号 |
US20050242822 |
申请日期 |
2005.10.03 |
| 申请人 |
NEURION PHARMACEUTICALS, INC. |
发明人 |
DOUGHERTY DENNIS A.;LESTER HENRY A.;NOWAK MARK W. |
| 分类号 |
C12Q1/68;C07H21/04;C07K14/705;C12P21/06 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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