发明名称 |
Selective high affinity polydentate ligands and methods of making such |
摘要 |
This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.
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申请公布号 |
US2006084115(A1) |
申请公布日期 |
2006.04.20 |
申请号 |
US20050055181 |
申请日期 |
2005.02.09 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
DENARDO SALLY;DENARDO GERALD;BALHORN RODNEY |
分类号 |
C40B40/10;C40B50/14;G01N33/48;G01N33/50;G01N33/53;G01N33/567;G01N33/574 |
主分类号 |
C40B40/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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