发明名称 |
Recombined polypeptide antibody or antibody fragment binds the ED-B domain of Fibronectin |
摘要 |
<p>Novel recombined polypeptide which is an antibody or an antibody fragment, which binds the ED-B domain of Fibronectin, and inhibits the interaction between the ED-B domain and its receptors. Independent claims are also included for the diagnostic and pharmaceutical applications of the recombinant polypeptide. The polypeptide has an affinity for the ED-B domain of K(D value equal to or less than 1 nM. ACTIVITY : Cytostatic. No biological data given. MECHANISM OF ACTION : Antibody therapy.</p> |
申请公布号 |
DE102004050101(A1) |
申请公布日期 |
2006.04.20 |
申请号 |
DE20041050101 |
申请日期 |
2004.10.14 |
申请人 |
SCHERING AG;MORPHOSYS AG |
发明人 |
PRASSLER, JOSEF;WEIDMANN, ARMIN;MENRAD, ANDREAS |
分类号 |
C07K16/44;A61K39/395;C07H21/00;C07K14/745;C07K19/00;C12N15/11 |
主分类号 |
C07K16/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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