Improved biocompatible liquid delivery compositions, which are useful for the formation of sustained release delivery systems for active agents, are provided. The compositions include liquid formulations of a biocompatible polymer or prepolymer in combination with a controlled release component. The controlled release component includes an active agent. These compositions may be introduced into the body of a subject in liquid form which then solidify or cure in situ to form a gelatinous controlled release implant or a film dressing. The liquid delivery compositions may also be employed ex situ to produce a gelatinous controlled release implant. Methods of forming a gelatinous controlled release implant and employing the liquid formulations in the treatment of a subject are also provided. <IMAGE>
申请公布号
DE69534780(D1)
申请公布日期
2006.04.20
申请号
DE1995634780
申请日期
1995.03.27
申请人
QLT USA INC., FORT COLLINS
发明人
YEWEY, GERALD L.;KRINICK, NANCY L.;DUNN, RICHARD L.;RADOMSKY, MICHAEL L.;BROUWER, GERBRAND;TIPTON, ARTHUR J.