A NOVEL PROCESS FOR THE PREPARATION OF NONRACEMIC LONG CHAIN a-AMINO ACIDS DERIVATIVES
摘要
<p>The present invention provides a process for the preparation of a nonracemic a-amino acid derivative from an optically active N-acyl lactam using an organometallic reagent to effect the opening of the ring followed by reduction of the ketone carbonyl to an alcohol or a methylene, or by a reductive amination to an amine, or by a ketalization reaction.</p>
