METHOD OF MONITORING ANTI-TUMOR ACTIVITY OF AN HDAC INHIBITOR
摘要
The present invention relates to the method of determining the anti-tumor activity of a histone deacetylase inhibitor by measuring the phosphorylation of the histone variant H2AX or the level of cytokeratin-18 fragment aa 387-397.
申请公布号
WO2006042035(A2)
申请公布日期
2006.04.20
申请号
WO2005US36025
申请日期
2005.10.07
申请人
AXYS PHARMACEUTICALS, INC.;BASS, KATHRYN E.;BRODER, SAMUEL E.;YOUNG, PETER R.
发明人
BASS, KATHRYN E.;BRODER, SAMUEL E.;YOUNG, PETER R.
