TRICYCLIC INDOLE DERIVATIVES FOR USE IN THE TREATMENT OF ALZHEIMER'S DISEASE
摘要
<p>The present invention relates to novel ketone compounds of formula (I) having Asp2 (ß-secretase, BACE1 or Memapsin-2) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated ß- amyloid levels or ß-amyloid deposits, particularly Alzheimer's disease.</p>
申请公布号
WO2006040148(A1)
申请公布日期
2006.04.20
申请号
WO2005EP11001
申请日期
2005.10.11
申请人
GLAXO GROUP LIMITED;DEMONT, EMMANUEL, HUBERT;REDSHAW, SALLY;WALTER, DARYL, SIMON
发明人
DEMONT, EMMANUEL, HUBERT;REDSHAW, SALLY;WALTER, DARYL, SIMON