发明名称 TRICYCLIC INDOLE DERIVATIVES FOR USE IN THE TREATMENT OF ALZHEIMER'S DISEASE
摘要 <p>The present invention relates to novel ketone compounds of formula (I) having Asp2 (ß-secretase, BACE1 or Memapsin-2) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated ß- amyloid levels or ß-amyloid deposits, particularly Alzheimer's disease.</p>
申请公布号 WO2006040148(A1) 申请公布日期 2006.04.20
申请号 WO2005EP11001 申请日期 2005.10.11
申请人 GLAXO GROUP LIMITED;DEMONT, EMMANUEL, HUBERT;REDSHAW, SALLY;WALTER, DARYL, SIMON 发明人 DEMONT, EMMANUEL, HUBERT;REDSHAW, SALLY;WALTER, DARYL, SIMON
分类号 A61K31/554;A61P25/28;C07D513/06 主分类号 A61K31/554
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