METHODS AND COMPOSITIONS FOR ENZYME-SPECIFIC ACTIVATION OF CARBOHYDRATE-CONJUGATED PRODRUGS
摘要
<p>Methods for the targeted activation of prodrugs by enzymes, which cleave a linkage between a carbohydrate conjugate and a drug. Means to target the activation of prodrugs to specific cells by linking the enzyme to an antibody molecule. Carbohydrate conjugates of geldanamycin.</p>
申请公布号
WO2006042056(A2)
申请公布日期
2006.04.20
申请号
WO2005US36061
申请日期
2005.10.07
申请人
THE OHIO STATE UNIVERSITY;SUN, DUXIN;WANG, PENG, GEORGE;MARTIN, EDWARD, JR.
