| 发明名称 |
BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR |
| 摘要 |
<p>Prodrugs of proton pump inhibitors of Formulas 1 through 4, where the symbols are as defined in the specification, and the R group includes at least one acidic group or its pharmaceutically acceptable salt, have improved aqueous solubility and bioavailability.</p> |
| 申请公布号 |
EP1556371(B1) |
申请公布日期 |
2006.04.19 |
| 申请号 |
EP20030765694 |
申请日期 |
2003.07.15 |
| 申请人 |
WINSTON PHARMACEUTICALS LLC;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;THE U.S. GOVERMENT (REPRESENTED BY) THE DEPARTMENT OF VETERANS AFFAIRS. |
发明人 |
GARST, MICHAEL E.;SACHS, GEORGE;SHIN, JAI MOO |
| 分类号 |
C07D401/00;C07D401/12;A61K31/4439;A61P1/04;A61P11/04;A61P11/06;A61P31/04;A61P43/00;C07D401/14;C07D409/14 |
主分类号 |
C07D401/00 |
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