Regulatory sequences of the human MCP-1 gene

摘要

Described is a nucleic acid molecule comprising (a) a nucleic acid sequence encoding the monocyte-chemoattractant-protein-1 (MCP-1) or a protein having the biological activity of the monocyte-chemoattractant-protein-1 (MCP-1) and (b) a hypersensitivity region. Also described are pharmaceutical compositions for the treatment of diseases associated with dysregulation of MCP-1 expression, e.g. atherosclerosis or cancer.