PROCESS FOR PREPARING FINE PARTICLE PHARMACEUTICAL FORMULATIONS

摘要

A process for preparing fine particle pharmaceutical formulations having imp roved throughput and producing greater uniformity of particle size comprises adding to the dry components of the formulation pr ior to the steps of wetting, extrusion and spheronizatio n, an extrusion aid material selected from pharmaceutically acceptable oils and w axes having a drop point between about 15 .degree.C and 115 .degree.C.