摘要 |
<p num="1"><br/><br/><br/>A process for producing a basic substance according to a fermentation <br/>technique, including culturing a microbe having the potency of producing a <br/>basic substance in a fermentation tank containing a liquid culture medium to <br/>thereby produce and accumulate the basic substance in the culture medium, <br/>characterized in that during at least a partial period of the entire culturing <br/>step, the ammonia concentration of the culture medium is regulated so as to <br/>fall within a given concentration range, thereby reducing the amount of <br/>sulfate ion and/or chloride ion used as a counter ion of the basic substance.<br/></p> |