发明名称 |
Methods and compositions for preventing vasospasm |
摘要 |
Methods and compositions for preventing or reducing vascular smooth muscle contraction are provided. Exemplary compositions comprise an MLCK inhibitor, for example wortmannin, in an amount effective to prevent or reduce vascular smooth muscle vasospams by about 90% for at least about 20 minutes. Methods for identifying other modulators of MLCK are also provided.
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申请公布号 |
US2006079573(A1) |
申请公布日期 |
2006.04.13 |
申请号 |
US20040006954 |
申请日期 |
2004.12.08 |
申请人 |
VINTEN-JOHANSEN JAKOB;KERENDI FARAZ |
发明人 |
VINTEN-JOHANSEN JAKOB;KERENDI FARAZ |
分类号 |
A61K31/366 |
主分类号 |
A61K31/366 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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