MEDICINAL COMPOSITION FOR PREVENTION OR TREATMENT OF PARASITIC PROTOZOAN INFECTION

摘要

A medicinal composition for the prevention or treatment of parasitic protozoan infection which has highly selective toxicity to parasitic protozoan infection and produces a high preventive or therapeutic effect thereon. The medicinal composition for the prevention or treatment of parasitic protozoan infection is characterized by containing a compound represented by the following general formula (1) as an active ingredient. [Chemical formula 1] (In the formula, R represents alkyl, aryl, or a heterocyclic group; A and B each independently represents a 5- or 6-membered ring containing at least one heteroatom or a fused ring comprising the 5- or 6-membered ring and one or more 3- to 8-membered rings fused therewith; Y represents S, O, Se, or -NR<SUP>1</SUP>- (R<SUP>1</SUP> represents alkyl, aryl or a heterocyclic group); L<SUP>1</SUP>, L<SUP>2</SUP>, L<SUP>3</SUP>, L<SUP>4</SUP>, and L<SUP>5</SUP> each independently represents methine; Q represents a physiologically acceptable anion; k is an integer of 0-2 which is necessary for making the charge of the whole molecule zero; and p and q each is 0-3, provided that p+q is an integer of 1-6.)