The present invention provides methods for the production of N-deacetylate N-sulfate derivatives of non-sulfated N-acetyl heparosan (HS) polysaccharides, compounds thus obtained and compositions comprising same. This invention also provides applications of N-dcacetylate N-sulfate derivatives of non-sulfated N-acetyl heparosan (HS) polysaccharides, and compositions comprising same, for use in controlling coagulation and treating thrombosis.
申请公布号
WO2006023487(A3)
申请公布日期
2006.04.13
申请号
WO2005US29095
申请日期
2005.08.16
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;ROSENBERG, ROBERT, D.;BALAGURUNATHAN, KUBERAN