| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a method and a device for controlling a local membrane potential in vivo which use a conductive material to produce a transient reversible cell depolarization and a spreading depression intentionally by using a safe method, and a method and a device for recovering nerve functions. <P>SOLUTION: The device for controlling the local membrane potential in vivo includes a variable magnetic field generating means for generating a variable magnetic field by current supply, a current supply part for supplying a current to the variable magnetic field generating means, and a variation potential converting means for applying stimuli of the variation potential in vivo by converting the variable magnetic field generated by the variable magnetic field generating means to a variation potential. A local potential varying device in vivo is characterized with the variation potential converting means that converts the variable magnetic field generated by the variable magnetic field generating means by the current supply from the current supply part to the variation potential at local parts in vivo and applies the variation potential in vivo for producing a transient reversible cell depolarization and a spreading depression. The production of the transient reversible cell depolarization and the spreading depression is used for treating neurodegenerative diseases and the impairment of brain functions, for mitigating various damage and disorder of cerebral nerves, and for recovering and regenerating the functions of the damaged brain and organs. <P>COPYRIGHT: (C)2006,JPO&NCIPI</p> |
