Neospora vaccine

摘要

The present invention provides a vaccine to protect a mammal against neosporosis comprising an immunologically effective amount of an homoganate prepared from cells of Neospora which is capable of inducing a protective response against neosporosis in a mammal, and a veterinarily acceptable carrier; wherein the Neospora cells from which the homogenate is prepared have been modified to delete the expression of one or more antigenic components normally associated with Neospora cells or a homogenate prepared therefrom; and antibodies specific to antigenic components present in homoganates of Neospora cells.