发明名称 |
Water-soluble drugs and methods for their production |
摘要 |
The present invention relates to water-soluble drugs, compositions containing same, and, in particular, a water-soluble analogue of geldanamycin. This invention also relates to a method of producing water-soluble analogues of water-insoluble drugs through derivatization and conjugation with a polar moiety via a thiol ether bond with a heterobifunctional linking molecule.
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申请公布号 |
US7026350(B2) |
申请公布日期 |
2006.04.11 |
申请号 |
US20040837785 |
申请日期 |
2004.05.03 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
HO DAVID K.;MANDLER RAYA;ALVARADO-LINDNER ADA BELINDA;DILLAH UPADHYAY KAYE B.;NEWMAN DAVID J. |
分类号 |
C07D225/04;A61K47/48;A61P35/00;C07D207/40;C07D207/416;C07D225/02;C07D403/12 |
主分类号 |
C07D225/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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