发明名称 |
Antitumor agents and process for producing the same |
摘要 |
Anticancer agents which contain as the active ingredient, a heme oxygenase inhibitory metalloporphyrin derivatives which are conjugated with amphipathic or water-soluble polymers (in particular, Zn-protoporphyrin (ZnPP) conjugated with polyethylene glycol). Because of being conjugated to amphipathic or water-soluble polymers, such as polyethylene glycol, the active ingredient can be administered by intravenous injection and can exert a remarkable anticancer effect owing to tumor selective delivery.
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申请公布号 |
US7026488(B2) |
申请公布日期 |
2006.04.11 |
申请号 |
US20040484726 |
申请日期 |
2004.02.17 |
申请人 |
MAEDA HIROSHI;SAWA TOMOHIRO |
发明人 |
MAEDA HIROSHI;SAWA TOMOHIRO |
分类号 |
C07D209/56;A61K31/409;A61K47/48;A61P35/00;A61P43/00;C07D487/22 |
主分类号 |
C07D209/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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