发明名称 |
COMPOSITION FOR IMPROVING EFFICIENCY OF DRUG DELIVERY |
摘要 |
Method and composition suitable for administering by direct convective interstitial infusion are disclosed. The method comprises: placing at least one direct convective interstitial infusion catheter in contact with the tissue, and pressuring the composition through the catheter. The composition is in a liquefied form having a viscosity above a predetermined value. The predetermined value is selected so as to improve infusion of the compositions into interstitial volumes of the tissue, while minimizing backflow of the compositions along an outer wall of the catheter or leakage into low resistance paths. It is demonstrated that high viscosity results in higher treatment efficiency. |
申请公布号 |
WO2006035444(A2) |
申请公布日期 |
2006.04.06 |
申请号 |
WO2005IL01049 |
申请日期 |
2005.09.29 |
申请人 |
TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.;MEDICAL RESEARCH FUND OF TEL AVIV SOURASKY MEDICAL CENTER;MARDOR, YAEL;RAM, ZVI |
发明人 |
MARDOR, YAEL;RAM, ZVI |
分类号 |
A61K49/00 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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