发明名称 RNA INTERFERENCE COMPOSITIONS AND METHODS
摘要 The invention provides isolated nucleic acids. For example, the invention provides isolated nucleic acids having at least one strand with both sense and antisense sequences that are complementary to each other. The invention also provides isolated nucleic acids having at least one strand that is a template for both sense and antisense sequences that are complementary to each other. In addition, the invention provides cells, viruses, and transgenic animals (e.g., transgenic non-human animals) containing one or more of the isolated nucleic acids provided herein as well as methods for using one or more of the isolated nucleic acids provided herein to reduce the level of an RNA (e.g., an mRNA) within a cell.
申请公布号 WO2005017127(A3) 申请公布日期 2006.04.06
申请号 WO2004US05400 申请日期 2004.02.23
申请人 THE PENN STATE RESEARCH FOUNDATION;CLAWSON, GARY, A.;PAN, WEI-HUA;XIN, PING 发明人 CLAWSON, GARY, A.;PAN, WEI-HUA;XIN, PING
分类号 C07H21/04;A61K31/19;A61K31/60;A61K38/00;A61K45/06;C12N15/113 主分类号 C07H21/04
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