发明名称 NOVEL PSEUDOMORPH OF VALACICLOVIR HYDROCHLORIDE
摘要 <p>The present invention relates to a stable novel pseudomorph of Valaciclovir hydrochloride and the process for its preparation by the debenzylation of 2-[(2-Amino-l,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl N- [(benzyloxy)carbonyl]L-valinate by bubbling hydrogen gas in presence of HCl, isolating the product in a mixture of ethanol and water followed by crystallization in aq.ethanol, drying under vacuum and allowing to adsorb moisture at ambient conditions.</p>
申请公布号 WO2006035452(A1) 申请公布日期 2006.04.06
申请号 WO2005IN00270 申请日期 2005.08.11
申请人 MATRIX LABORATORIES LTD;CHAVA, SATYANARAYANA;GORANTLA, SEETA, RAMANJANEYULU;ABBINENI, JYOTHI, BASU 发明人 CHAVA, SATYANARAYANA;GORANTLA, SEETA, RAMANJANEYULU;ABBINENI, JYOTHI, BASU
分类号 (IPC1-7):C07D473/18;A61K31/522 主分类号 (IPC1-7):C07D473/18
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