发明名称 |
Dinucleotide inhibitors of de novo RNA polymerases for treatment or prevention of viral infections |
摘要 |
Contemplated dinucleotide compounds have a general structure of A-B and inhibit synthesis of an RNA-dependent polymerase that initiates RNA replication de novo. In preferred dinucleotides, A comprises a purine or modified purine heterocyclic base and B comprises a pyrimidine or modified pyrimidine heterocyclic base.
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申请公布号 |
US2006074035(A1) |
申请公布日期 |
2006.04.06 |
申请号 |
US20030418662 |
申请日期 |
2003.04.17 |
申请人 |
HONG ZHI;ZHONG WEIDONG;AN HAOYUN;BARAWKAR DINESH |
发明人 |
HONG ZHI;ZHONG WEIDONG;AN HAOYUN;BARAWKAR DINESH |
分类号 |
A61K31/7076;C07H19/04 |
主分类号 |
A61K31/7076 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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