发明名称 |
SYSTEMS AND METHODS OF IDENTIFYING BIOMARKERS FOR SUBSEQUENT SCREENING AND MONITORING OF DISEASES |
摘要 |
<p>A system for generating an image of ultrastructural biomarkers from a biological sample is provided. The system includes a grid onto which a sample to be imaged may be placed and a cryogenic reservoir into which the grid and sample may be immersed for vitrification of the sample. The system also includes a stage onto which the grid and sample may be situated for subsequent imaging in a high contrast imager to permit identification of ultrastructural biomarkers therein. A method for generating an image of ultrastructural biomarkers from a biological sample is also provided. The generated image of ultrastructural biomarkers may be used subsequently for screening and monitoring diseases, evaluating drug and therapeutic efficacy, and assessing risks associated with a drug or therapeutic candidate, among other things.</p> |
申请公布号 |
WO2006036771(A2) |
申请公布日期 |
2006.04.06 |
申请号 |
WO2005US34097 |
申请日期 |
2005.09.22 |
申请人 |
VITRIMARK, INC.;BOSE, ARIJIT;AZIZ, NAZNEEN |
发明人 |
BOSE, ARIJIT;AZIZ, NAZNEEN |
分类号 |
C12Q1/00;C12M1/34;C12Q1/68 |
主分类号 |
C12Q1/00 |
代理机构 |
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代理人 |
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地址 |
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