发明名称 |
FUSED FURAN DERIVATIVE AND USE THEREOF |
摘要 |
<p>A compound represented by the formula (I) [wherein R<SUP>1</SUP> represents optionally substituted amino; R<SUP>2</SUP> represents optionally substituted carbamoyl; one of X and Y represents carbon and the other represents carbon or nitrogen; ---- indicates a single bond or double bond; ring A represents an optionally substituted monocycle; and ring B represents an optionally substituted aromatic ring], a salt thereof, or a prodrug of either; and a medicine containing the compound, salt, or prodrug. The compound is a novel fused furan derivative which differs from any known compound in chemical structure and has I?B kinase inhibitory activity, NF-?B inhibitory activity, TNF-a-production inhibitory activity, etc.</p> |
申请公布号 |
WO2006036031(A1) |
申请公布日期 |
2006.04.06 |
申请号 |
WO2005JP18586 |
申请日期 |
2005.09.30 |
申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED;IKEURA, YOSHINORI;YOSHIDA, MASATO;SUGIYAMA, HIDEYUKI |
发明人 |
IKEURA, YOSHINORI;YOSHIDA, MASATO;SUGIYAMA, HIDEYUKI |
分类号 |
A61K31/381;C07D307/92;A61K31/34;A61K31/343;A61K31/4365;A61P1/02;A61P1/04;A61P1/16;A61P1/18;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/10;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P19/06;A61P19/10;A61P21/00;A61P21/04;A61P25/00;A61P25/28;A61P27/16;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P37/04;A61P37/06;A61P37/08;A61P43/00;C07D307/93;C07D493/04;C07D495/04;C07D495/14 |
主分类号 |
A61K31/381 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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