摘要 |
<p>A compound having SGLT1 and/or SGLT2 inhibitory activity which is usable as a preventive or therapeutic agent for diabetes, postprandial hyperglycemia, impaired glucose tolerance, complications of diabetes, obesity, etc. It is a 1-(ß-D-glycopyranosyl)-3-substituted nitrogenous heterocyclic compound represented by the general formula (I), a prodrug or pharmacologically acceptable salt thereof, or a hydrate or solvate of either. Also provided is an SGLT inhibitor containing any of these. [In the formula, ring A represents optionally substituted aryl or heteroaryl; Q<SUP>1</SUP> to Q<SUP>5</SUP> each independently represents either a carbon atom having a hydrogen atom or substituent bonded thereto or a nitrogen atom; E represents a single bond, alkylene, -O-, -S-, or -NH-; and R represents methyl, ethyl, fluoromethyl, or hydroxymethyl.]</p> |
申请人 |
KISSEI PHARMACEUTICAL CO., LTD.;OHNO, KOHSUKE;TERANISHI, HIROTAKA;KIKUCHI, NORIHIKO |
发明人 |
TERANISHI, HIROTAKA;KIKUCHI, NORIHIKO |