发明名称 |
POROUS COMPOSITE CONTAINING CALCIUM PHOSPHATE AND PROCESS FOR PRODUCING THE SAME |
摘要 |
<p>A porous composite comprising a porous layer containing a calcium phosphate ceramic, and a dense layer formed on part of the porous layer and having a smaller average pore size than that of the porous layer. The porous composite can be produced by (1) introducing a slurry containing a calcium phosphate ceramic/collagen composite and collagen into a molding die having a high thermal conductivity, (2) rapidly freezing and drying the slurry in the molding die, to form a porous body comprising a porous layer and a dense layer formed on the porous layer, (3) cross-linking collagen in the porous body, and (4) removing the dense layer except for a portion thereof on a surface coming into contact with a soft tissue when implanted in a human body, so that the porous layer is exposed.</p> |
申请公布号 |
EP1642599(A1) |
申请公布日期 |
2006.04.05 |
申请号 |
EP20040745321 |
申请日期 |
2004.05.26 |
申请人 |
HOYA CORPORATION;NATIONAL INSTITUTE FOR MATERIALS SCIENCE |
发明人 |
KAWAMURA, KATSUMI;NAKAJIMA, TAKEHIKO;SHOJI, DAISUKE;TANAKA, JUNZO;KIKUCHI, M.;IKOMA, T. |
分类号 |
A61K6/033;A61L27/12;A61L27/42;A61L27/56;(IPC1-7):A61L27/12;A61L27/40;C01B25/32 |
主分类号 |
A61K6/033 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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