发明名称 Pyridine and pyrimidine derivatives
摘要 The present invention provides compounds of formula (I) wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4 </SUP>and X are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.
申请公布号 US7022718(B2) 申请公布日期 2006.04.04
申请号 US20050037989 申请日期 2005.01.18
申请人 HOFFMANN-LA ROCHE INC. 发明人 BOEHRINGER MARKUS;LOEFFLER BERND MICHAEL;PETERS JENS-UWE;STEGER MATTHIAS;WEISS PETER
分类号 C07D213/74;A61K31/4418;A61K31/443;A61K31/505;A61K31/506;A61K31/5377;A61P1/04;A61P3/00;A61P3/04;A61P3/10;A61P7/10;A61P9/12;C07D213/73;C07D239/42;C07D401/04;C07D403/04;C07D405/04;C07D409/04 主分类号 C07D213/74
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