发明名称 |
Methods and materials for optimization of electronic transportation and hybridization reactions |
摘要 |
Methods for the transport and hybridization of a nucleic acid on an electrode device by providing a low conductivity buffer with a reducing agent to the device. The low conductivity buffer may also contain a zwitterion. A current and voltage is applied to a location of the device to effect electrophoretic transportation of the nucleic acid towards the location. The nucleic acid is then hybridized to a nucleic probed located at the location. The reducing agent in the low conductivity buffer may also be acting as a chaotropic agent.
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申请公布号 |
US2006065531(A1) |
申请公布日期 |
2006.03.30 |
申请号 |
US20050234054 |
申请日期 |
2005.09.22 |
申请人 |
NANOGEN, INC |
发明人 |
SMOLKO DANIEL D.;SWANSON PAUL D.;HODKO DALIBOR;CANTER DAVID;HAIGIS ROBERT W.;PATTERSON TRICIA |
分类号 |
C07K1/26;G01N27/447 |
主分类号 |
C07K1/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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