MATERIALS AND METHODS FOR FOLATE BIOFORTIFICATION IN PLANTS

摘要

The subject invention concerns materials and methods for enhancing folate content of plants. In one embodiment of a method of the invention, a plant is engineered to increase levels of pteridines in the plant. In an exemplified embodiment, a plant is transformed with a polynucleotide encoding a mammalian-type GCHI polpeptide or a bacterial GCHI polypeptide that is free of feedback control when expressed in plants. The subject invention also concerns plants having enhanced folate content. In one embodiment, a plant of the invention comprises and expresses a polynucleotide encoding a mammalian-type GCHI polypeptide or a bacterial GCHI polypeptide that is free of feedback control when expressed in the plant.