发明名称 |
USE OF C-KIT INHIBITORS FOR TREATING FIBROSIS |
摘要 |
The present invention relates to a method for treating fibrosis and related disorders comprising administering a compound capable of depleting mast cell or a compound inhibiting mast cells degranulation, to a human in need of such treatment. Such compounds can be chosen from c-kit inhibitors and more particularly non-toxic, selective and potent c-kit inhibitors. Preferably, said inhibitor is unable to promote death of IL-3 dependent cells cultured in presence of IL-3. |
申请公布号 |
WO2005102346(A3) |
申请公布日期 |
2006.03.30 |
申请号 |
WO2005IB01391 |
申请日期 |
2005.04.19 |
申请人 |
AB SCIENCE;MOUSSY, ALAIN;KINET, JEAN-PIERRE |
发明人 |
MOUSSY, ALAIN;KINET, JEAN-PIERRE |
分类号 |
A61K31/4178;A61K31/427;A61K31/4433;A61K31/4436;A61K31/497;A61K31/506;A61K31/517;A61K31/5355 |
主分类号 |
A61K31/4178 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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