摘要 |
<p>Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, wherein A, R<SUP>1</SUP>, X and Y are defined herein, are useful in the treatment of tumors and cancers such as mastocytosis/mast cell leukemia, gastrointestinal stromal tumors (GIST), germ cell tumors, small cell lung carcinoma (SCLC), sinonasal natural killer/T-cell lymphoma, testicular cancer (seminoma), thyroid carcinoma, malignant melanoma, ovarian carcinoma, adenoid cystic carcinoma, acute myelogenous leukemia (AML), breast carcinoma, pediatric T-cell acute lymphoblastic leukemia, neuroblastoma, mast cell leukemia, angiosarcoma, anaplastic large cell lymphoma, endometrial carcinoma, and prostate carcinoma.</p> |
申请人 |
OSI PHARMACEUTICALS, INC.;LI, AN-HU;DONG, HANQING;ZHANG, TAO |
发明人 |
LI, AN-HU;DONG, HANQING;ZHANG, TAO |