POLYNUCLEOTIDES AND POLYPEPTIDES ASSOCIATED WITH TROPHOBLASTCELL DEATH, DIFFERENTIATION, INVASION, AND/OR CELL FUSION AND TURNOVER

摘要

The invention relates to polypeptides and polynucleotides associated with trophoblast cell death, differentiation, invasion, and/or cell fusion and turnover, and uses of same in the prevention, diagnosis and treatment of conditions requiring regulation of trophoblast cell death, differentiation, invasion, and/or cell fusion and turnover. In particular aspects, diagnostic methods are disclosed for evaluating conditions such as preeclampsia utilizi ng matador polypeptides and polynucleotides encoding same.