发明名称 |
Pharmaceutical compositions for the treatment of diseases related to neurotrophines |
摘要 |
The present invention refers to pharmaceutical preparations including as active compounds 3-aza-bicyclo[3.2.1]octane derivatives of general formula (I) and/or their dimers of general formula (II) and (III) acting as agonists of human neurotrophines. Therefore, such compounds of formula (I), (II) and (III) are useful for treatment of diseases in which the neurotrophine functions are involved in defect, particularly of Nerve Growth Factor (NGF), such as neurodegenerative diseases of central nervous system (CNS), acquired immunodeficiency due to a reduced NGF biodisponibility, or morbous conditions in which the stimulus of neoangiogenesis process is convenient.
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申请公布号 |
US2006069092(A1) |
申请公布日期 |
2006.03.30 |
申请号 |
US20040518689 |
申请日期 |
2004.12.17 |
申请人 |
GUARNA ANTONIO;COZZOLINO FEDERICO;TORCIA MARCIA;GARACI ENRICO |
发明人 |
GUARNA ANTONIO;COZZOLINO FEDERICO;TORCIA MARCIA;GARACI ENRICO |
分类号 |
A61K31/538;C07D498/08;A61K31/5386;A61K31/55;A61K31/551;A61K31/553;A61K31/554;A61P1/04;A61P9/00;A61P17/02;A61P21/00;A61P25/00;A61P25/08;A61P25/14;A61P25/28;A61P27/02;A61P27/06;A61P29/00;A61P35/00;A61P37/04;A61P39/02;A61P43/00;C07D519/00 |
主分类号 |
A61K31/538 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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