| 发明名称 |
Viral vectors |
| 摘要 |
A Human Immunodeficiency Virus (HIV-2) vector having a mutation within a packaging signal such that viral RNA is not packaged within an HIV-2 capsid is described. A further vector comprises an HIV-2 packaging signal and a heterologous gene capable of being expressed in the vector. These vectors may be co-transfected into a host cell to produce HIV-2 virus particles capable of expressing a heterologous gene.
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| 申请公布号 |
US2006067948(A1) |
申请公布日期 |
2006.03.30 |
| 申请号 |
US20050473412 |
申请日期 |
2005.12.12 |
| 申请人 |
ALLEN JANE F;GRIFFIN STEPHEN D C;LEVER ANDREW MICHAEL L |
发明人 |
ALLEN JANE F.;GRIFFIN STEPHEN D.C.;LEVER ANDREW MICHAEL L. |
| 分类号 |
A61K39/21;C12N15/09;A61K35/00;A61K38/00;A61K39/00;A61K48/00;A61P31/18;C12N7/00;C12N7/04;C12N15/867 |
主分类号 |
A61K39/21 |
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