| 发明名称 |
METHOD OF PREPARING POLY(ADP-RIBOSE) POLYMERASES INHIBITORS |
| 摘要 |
<p>The invention relates to a new and convergent route to small molecule inhibitors of poly(ADP-ribose) polymerase, such as 8-fluoro-2{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino [5,4,3-cd]indol-6-one, via a key Sonogashira coupling reaction and a Cul-promoted indole formation.</p> |
| 申请公布号 |
WO2006033003(A1) |
申请公布日期 |
2006.03.30 |
| 申请号 |
WO2005IB02881 |
申请日期 |
2005.09.12 |
| 申请人 |
PFIZER, INC.;CANCER RESEARCH TECHNOLOGY LTD.;MA, CHUNRONG;NAYYAR, NARESH;STANKOVIC, NEBOJSA, SLOBODAN |
发明人 |
MA, CHUNRONG;NAYYAR, NARESH;STANKOVIC, NEBOJSA, SLOBODAN |
| 分类号 |
(IPC1-7):C07D487/06;C07D487/06;C07D209:00;C07D223:00 |
主分类号 |
(IPC1-7):C07D487/06 |
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