发明名称 COMBINATION THERAPY WITH GLATIRAMER ACETATE AND MITOXANTRONE FOR THE TREATMENT OF MULTIPLE SCLEROSIS
摘要 The subject invention provides a method of treating a subject afflicted with a form of multiple sclerosis comprising periodically administering to the subject an amount of glatiramer acetate and an amount of mitoxantrone, wherein the amounts when taken together are effective to alleviate a symptom of the form of multiple sclerosis in the subject so as to thereby treat the subject. The subject invention also provides a package comprising glatiramer acetate, mitoxantrone and instructions for use of the together to alleviate a symptom of a form of multiple sclerosis in a subject. Additionally, the subject invention provides a pharmaceutical composition comprising an amount of glatiramer acetate and an amount of mitoxantrone, wherein the amounts when taken together are effective to alleviate a symptom of a form of multiple sclerosis in a subject. The subject invention further provides a pharmaceutical combination comprising separate dosage forms of an amount of glatiramer acetate and an amount of mitoxantrone, which combination is useful to alleviate a symptom of a form of multiple sclerosis in a subject.
申请公布号 EP1638589(A2) 申请公布日期 2006.03.29
申请号 EP20040752284 申请日期 2004.05.14
申请人 TEVA PHARMACEUTICAL INDUSTRIES LIMITED 发明人 VOLLMER, TIMOTHY
分类号 A61K38/02;A61K;A61K31/137;A61K38/00;A61P25/28;(IPC1-7):A61K38/00 主分类号 A61K38/02
代理机构 代理人
主权项
地址