| 摘要 |
<p>A compound represented by the formula (1):
(wherein X represents sulfur or oxygen; R 1 and R 2 each represents a group represented by the formula -Y 3 -Z, etc.; Y 3 represents a single bond or (un)substituted alkylene; Y 1 and Y 2 each represents (un)substituted alkylene; Z represents hydrogen, an (un)saturated monocyclic heterocyclic group, etc.; M represents carboxy, etc.; Q represents o-phenylene, etc.; and A represents an (un)saturated monocyclic hydrocarbon group, etc.), a prodrug thereof, or a pharmaceutically acceptable salt of either. They are compounds having chymase inhibitory activity and useful as a therapeutic agent for hypertension, cardiac failure, etc.</p> |
