发明名称 |
A stabilized aqueous (6S)-folinic acid preparation for injection |
摘要 |
The present invention provides a stabilized aqueous preparation for injection containing 5-formyl-(6S)-tetrahydrofolic acid or a pharmacologically acceptable salt thereof as an active ingredient and a method of stabilizing 5-formyl-(6S)-tetrahydrofolic acid or a pharmacologically acceptable salt thereof. An aqueous preparation containing 5-formyl-(6S)-tetrahydrofolic acid or a pharmacologically acceptable salt thereof shows extremely excellent preservation stability in the presence of a pH regulator and an antioxidant.
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申请公布号 |
EP1640008(A1) |
申请公布日期 |
2006.03.29 |
申请号 |
EP20050019715 |
申请日期 |
2005.09.09 |
申请人 |
NIPRO CORPORATION |
发明人 |
MIYAJI, TATSUAKI;SHIROUCHI, YUTAKA;SATO, MAKOTO;FUJISAWA, YUKI |
分类号 |
A61K31/522;A61K9/08 |
主分类号 |
A61K31/522 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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