Process for preperation of a sterile suspension of corticosteroid particles for the administration by inhalation

摘要

A process for the preparation of aqueous suspensions of sterile micronized drug particles, in particular corticosteroid, to be administered by inhalation, which produces homogenous dispersions of particles characterized by optimal size and size distribution is disclosed. The process is carried out by using a turboemulsifier equipped with a high-power turbine and connected to a loading hopper.