发明名称 |
Conjugates of TC complexes and targeting moieties and their use in MRI diagnostic |
摘要 |
The present invention relates to improved <99m>Tc radiometal complex compositions of aza-diaminedioxime ligands, together with radiopharmaceutical preparations containing them, and kits for the preparation of the radiopharmaceuticals. The technetium metal complexation chemistry of aza-diaminedioxime-targeting molecule chelator conjugates is shown to give rise to a multiplicity of technetium species. The present invention provides an improved aza-diaminedioxime conjugate technetium metal complex composition in which the presence of the less desirable technetium species is suppressed. |
申请公布号 |
ZA200502835(B) |
申请公布日期 |
2006.03.29 |
申请号 |
ZA20050002835 |
申请日期 |
2006.01.19 |
申请人 |
GE HEALTHCARE LIMITED |
发明人 |
GEORG BRAUERS;BARNETT, DAVID, J.;LEWIS, JOANNE, S.;GILLIAN FARRAR;WADSWORTH, HARRY, J. |
分类号 |
A61K;A61K51/08;C07K14/47;C07K14/81 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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