摘要 |
<p>Methods and apparatus for calculating a parameter of mass exchange of a solute fluid are disclosed including passing the solute in a predetermined volume of the fluid on one side of a semi-permeable membrane in a dialyzer, passing an exchange fluid on the other side of the semi-permeable membrane, obtaining a concentration curve by repeatedly measuring the concentration of a solute such as urea in the mass exchange fluid, fitting an approximate curve having a logarithm comprising a substantially straight line with at least a portion of a concentration curve, determining a parameter of the approximation curve, and calculating the mass of urea in the predetermined volume of fluid by the formula m=(Qdxcd)/P where P is the mass of the urea, Qd is the flow rate of the exchange fluid, Cd is the concentration of the urea in the exchange fluid, and P is the parameter.</p> |