发明名称 |
PYRID (2, 1-A) - ISOQUINOLINE DERIVATIVES AS DPP-IV INHIBITORS |
摘要 |
The present invention provides compounds of formula (I) wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3 </SUP>and R<SUP>4 </SUP>are as indicated in the description, or a pharmaceutically acceptable salt thereof. The compounds are useful for the treatment of diseases which are associated with DPP-IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance. |
申请公布号 |
EP1638970(A1) |
申请公布日期 |
2006.03.29 |
申请号 |
EP20040739841 |
申请日期 |
2004.06.11 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BOEHRINGER, MARKUS;KUHN, BERND;MATTEI, PATRIZIO;NARQUIZIAN, ROBERT |
分类号 |
C07D471/06;A61P3/10;C07D471/04 |
主分类号 |
C07D471/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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