发明名称 Chimeric IL-10
摘要 Disclosed are chimeric proteins having a cytokine fused to an enzymatically inactive polypeptide which increases the circulating half-life of the cytokine. The chimeric proteins are useful for treating, inhibiting, or preventing a variety of conditions, including septic shock, granulomatous disorders, Type I diabetes, and various cancers (e.g., multiple myeloma) in a patient.
申请公布号 US7018626(B2) 申请公布日期 2006.03.28
申请号 US20020145517 申请日期 2002.05.14
申请人 BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 发明人 STROM TERRY B.;ZHENG XIN XIAO;STEELE ALAN
分类号 C07K14/52;A61K38/00;A61K38/20;C07K16/46;C12N15/24;C12N15/62 主分类号 C07K14/52
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