摘要 |
A compound represented by the following formula (1): (1) [wherein R1 represents hydrogen, chlorine, or hydroxy; X1...X2represents -CH(R2)-CH(R 3)-, etc., wherein R2 and R3 each represents hydrogen or alkyl; A1, A11, A2, and A21 each represents hydrogen or alkyl; Y represents - CH(A3)-, -CH(A3)-C(A4)(A41)-, etc. or represents a single bond, wherein A3, A4, and A 41 each represents hydrogen or alkyl; and Z represents hydroxy or - N(A6)(A61), wherein A6represents hydrogen or alkyl and A61 represents hydrogen, alkyl, aralkyl, etc.] or a salt of the compound. The compound or salt potently inhibits the phosphorylation of myosin-control light chains.
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