| 摘要 |
PROBLEM TO BE SOLVED: To provide a diagnostic imaging method for noninvasively and correctly monitoring the state of a specific tissue or tissue component. SOLUTION: The method for contrast-enhanced diagnostic imaging of the specific tissue or tissue component being subjected or having been subjected to an interventional therapy comprises (a) a step for prescribing for a patient a contrast agent capable of binding to a targeted tissue or tissue component and exhibiting a special affinity to the tissue or tissue component, the contrast agent comprising an image-enhancing moiety (IEM) and a state-depending tissue binding moiety (SDTBM); (b) a step for subjecting the patient to one of MRI imaging, ultraviolet imaging, visible light imaging and infrared imaging; and (c) a step for monitoring the characteristic imaged signal of the contrast agent to decide whether the interventional therapy is completed or not. COPYRIGHT: (C)2006,JPO&NCIPI
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